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[Measles control in developing countries]

F T Cutts1, F Dabis

  • 1London School of Hygiene and Tropical Medicine, Grande-Bretagne.

Sante (Montrouge, France)
|May 1, 1994
PubMed
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Measles vaccination significantly reduces disease but can shift outbreaks to older children and vaccinated individuals. Continued surveillance and strategies are vital to address evolving measles epidemiology.

Area of Science:

  • Epidemiology
  • Public Health
  • Immunization Programs

Background:

  • Measles vaccination has greatly reduced global disease and deaths.
  • Increased vaccination coverage alters measles epidemiology, shifting cases to older age groups.

Purpose of the Study:

  • To analyze changes in measles epidemiology with increased vaccination coverage.
  • To identify reasons for measles outbreaks in populations with moderate to high vaccination rates.

Main Methods:

  • Analysis of epidemiological data on measles cases and vaccination coverage.
  • Review of factors contributing to measles outbreaks in diverse settings.

Main Results:

  • Measles vaccination leads to accumulation of susceptible individuals and "post-honeymoon" outbreaks.

Related Experiment Videos

  • Outbreaks occur in pockets of low coverage, among vaccine refusers, and due to vaccine failures.
  • Vaccine efficacy can be compromised by poor storage, leading to larger outbreaks.

    • Conclusions:

    • Despite progress, measles outbreaks persist due to epidemiological shifts and vulnerabilities.
    • Additional strategies are needed to manage measles in populations with high vaccination coverage.
    • Addressing vaccine failures and ensuring proper vaccine handling are crucial for future measles control.