Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Inotropic agents

J L Vincent1, J C Preiser

  • 1Department of Intensive Care, Erasme University Hospital, Free University of Brussels, Belgium.

New Horizons (Baltimore, Md.)
|February 1, 1993
PubMed
Summary
This summary is machine-generated.

Inotropic agents like dopamine and dobutamine aid tissue perfusion but their impact on oxygen extraction is uncertain. Therapy requires monitoring blood pressure and organ metabolic function.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Core competencies in critical care for general medical practitioners in South Africa: A Delphi study.

The Southern African journal of critical care : the official journal of the Critical Care Society·2024
Same author

A systematic review and meta-analysis of the clinimetric properties of the core outcome measurement instruments for clinical effectiveness trials of nutritional and metabolic interventions in critical illness (CONCISE).

Critical care (London, England)·2023
Same author

Core outcome measures for clinical effectiveness trials of nutritional and metabolic interventions in critical illness: an international modified Delphi consensus study evaluation (CONCISE).

Critical care (London, England)·2022
Same author

[Advocacy for an improved training in clinical nutrition during the medical cursus].

Revue medicale de Liege·2021
Same author

Intensive care units follow-up: a scoping review protocol.

BMJ open·2020
Same author

[Religious and cultural aspects of organ transplantation].

Revue medicale de Bruxelles·2018
Same journal

Palliative care in the intensive care unit.

New horizons (Baltimore, Md.)·2001
Same journal

An international perspective on the treatment of pediatric shock: the Brazilian experience.

New horizons (Baltimore, Md.)·1998
Same journal

Nutrition and shock in pediatric patients.

New horizons (Baltimore, Md.)·1998
Same journal

Recent advances in pediatric cardiopulmonary resuscitation and advanced life support.

New horizons (Baltimore, Md.)·1998
Same journal

Potential protective role of the heat shock response in sepsis.

New horizons (Baltimore, Md.)·1998
Same journal

Molecular biology of septic shock.

New horizons (Baltimore, Md.)·1998
See all related articles

Area of Science:

  • Critical care medicine
  • Pharmacology
  • Physiology

Background:

  • Fluid administration is primary for hemodynamic stability.
  • Inotropic agents increase tissue perfusion pressure and oxygen delivery (DO2) when fluids are insufficient.
  • Septic shock resuscitation often uses dopamine; norepinephrine is an option for cardiovascular collapse or RV failure.

Purpose of the Study:

  • To review the role of inotropic agents in critical care.
  • To discuss current and potential therapeutic options for improving tissue oxygenation.
  • To emphasize the importance of monitoring organ function alongside systemic blood pressure.

Main Methods:

  • Literature review of inotropic agents used in critical care.
  • Discussion of adrenergic and nonadrenergic agents.

Related Experiment Videos

  • Emphasis on clinical monitoring parameters.

    • Main Results:

    • Dopamine is a primary choice for septic shock resuscitation.
    • Dobutamine is favored for increasing DO2.
    • The effect of these agents on tissue oxygen extraction remains debated.
    • Other agents like dopexamine and phosphodiesterase inhibitors show potential.
    • Norepinephrine has specific indications in cardiovascular collapse and RV failure.

    Conclusions:

    • Inotropic therapy choice depends on clinical context and patient response.
    • Systemic blood pressure alone is insufficient to guide therapy.
    • Repeated assessment of organ metabolic function is crucial for effective inotropic support.