[Changes in erythrocyte fluidity, fragility and deformability and serum lipid peroxide content in early burn period]

We have observed RBC membrane fluidity, serum lipid peroxide, RBC deformability and fragility in 10 burn patients on PBD 2.3-5 and 6-10. The results showed that there was a reduction of RBC membrane fluidity and, on the contrary, there was an elevation in the contents of serum lipid peroxide and RBC deformability and fragility (All P < 0.01). We consider that damage of RBC membrane by free radicals may be one of the reasons of the above changes, and anti-free radical drugs may be beneficial in protecting RBC structure and functions and blood circulation.