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Bioactive substances in food: identification and potential uses

D D Kitts1

  • 1Department of Food Science, University of British Columbia, Vancouver, Canada.

Canadian Journal of Physiology and Pharmacology
|April 1, 1994
PubMed
Summary

Bioactive food substances offer health benefits beyond nutrition, influencing physiological and immunological effects. Research explores their mechanisms, biotechnologies, and consumer acceptance for specialized food products.

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Area of Science:

  • Food Science
  • Biochemistry
  • Pharmacology

Background:

  • Bioactive food constituents are extranutritional compounds found naturally or produced during food processing.
  • These substances, including phytochemicals and food-derived peptides, exert physiological, behavioral, and immunological effects.
  • Evidence suggests roles in cancer chemoprevention and hyperlipidemia control.

Purpose of the Study:

  • To discuss the physicochemical mechanisms of action of food-derived bioactive substances.
  • To explore biotechnologies used in developing these products.
  • To address consumer and regulatory acceptance issues.

Main Methods:

  • Review of epidemiological and animal studies on phytochemicals.
  • Analysis of physicochemical properties of food-derived peptides.

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  • Identification and purification of biologically active peptides from various protein sources.
  • Discussion of biotechnological approaches and regulatory considerations.

    • Main Results:

    • Phytochemicals can modulate enzymes involved in xenobiotic metabolism and cholesterol synthesis.
    • Food-derived peptides influence nutrient absorption, intestinal transit, and exhibit immunostimulating and antihypertensive activities.
    • Therapeutic proteins from animal sources show potential for specialized food products.

    Conclusions:

    • Bioactive food substances possess diverse health-promoting properties.
    • Biotechnologies are advancing the development of functional foods incorporating these compounds.
    • Consumer and regulatory acceptance are key factors for market integration.