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Related Experiment Videos

Systematic intervention for elderly inpatients with delirium: a randomized trial

M G Cole1, F J Primeau, R F Bailey

  • 1Department of Psychiatry, St. Mary's Hospital Center, Montreal, Que.

CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne
|October 1, 1994
PubMed
Summary

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A systematic intervention for elderly inpatients with delirium showed small benefits. While cognitive scores improved initially, the effects diminished over time, with no significant impact on other outcomes.

Area of Science:

  • Geriatrics
  • Internal Medicine
  • Psychiatry
  • Clinical Research

Background:

  • Delirium is a common and serious condition in elderly inpatients.
  • Early detection and intervention are crucial for managing delirium.
  • The effectiveness of systematic interventions in this population requires further assessment.

Purpose of the Study:

  • To evaluate a systematic intervention strategy for elderly patients experiencing delirium.
  • To assess the impact of the intervention on cognitive function, behavioral symptoms, and clinical outcomes.

Main Methods:

  • A randomized controlled trial was conducted in a university-affiliated hospital.
  • 88 elderly inpatients (≥75 years) diagnosed with delirium were enrolled.

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  • The intervention group received specialized geriatric/psychiatric consultation and liaison nurse follow-up; the control group received standard care.

    • Main Results:

    • The intervention group showed initial improvement in Short Portable Mental Status Questionnaire (SPMSQ) scores at 2 weeks, but this difference was not sustained.
    • Crichton Geriatric Behavioural Rating Scale (CGBRS) scores improved more in the intervention group, though not reaching statistical significance at 8 weeks (p=0.06).
    • No significant differences were observed in the use of restraints, length of hospital stay, discharge destination, or mortality rates between groups.

    Conclusions:

    • Systematic detection and intervention for delirium in elderly inpatients yielded minimal beneficial effects.
    • The study suggests that while some cognitive improvements may occur, the overall impact on key clinical outcomes is limited.
    • Further research may be needed to optimize intervention strategies for delirium in this vulnerable population.