[Clinical investigation of erythrocyte function in patients with lung cancer]

With a yeast-erythrocyte-SPA rosette method, the function of erythrocyte immune adherence was determined in 49 cases of lung cancer, 20 cases of benign pulmonary diseases and 60 healthy persons. By means of simple morphologic method and pyrogallol autoxication method, the function of erythrocyte enhancing neutrophils phagocytosis and the activity of RBC-CuZnSOD were measured in some of these subjects. It was found that both the function of red cell immune adherence and the effect of erythrocyte enhancing phagocytosis in the patients with lung cancer were significantly weaker than in the cases of benign pulmonary diseases and the healthy subjects. The function of erythrocyte immune adherence tended to recover after effective surgical treatment. In comparison with the healthy persons, the activity of RBC-CuZnSOD was significantly lower in the patients with lung cancer. The mechanism and clinical significance of the changes in erythrocyte function were discussed.