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Laboratory medicine in ulcer disease
M Plebani1, F Vianello, F Di Mario
1Institute of Laboratory Medicine, University-Hospital of Padova, Italy.
Clinical Biochemistry
|June 1, 1994
Summary
Laboratory tests aid in managing ulcer disease by identifying Helicobacter pylori infection and high acid output. These investigations improve patient care and diagnostic strategies for peptic ulcers.
Area of Science:
- Gastroenterology
- Clinical Pathology
- Internal Medicine
Background:
- The role of laboratory medicine in ulcer disease management is not well-established.
- Increasing evidence supports the clinical utility of specific laboratory tests.
Purpose of the Study:
- To review the clinical value and cost-benefit ratio of laboratory tests in ulcer disease.
- To outline the role of these tests in diagnostic algorithms.
Main Methods:
- Review of existing literature on laboratory tests for ulcer disease.
- Analysis of tests investigating gastric secretory function, gastrointestinal hormones, and Helicobacter pylori infection.
Main Results:
- Laboratory tests can identify H. pylori positive subjects, high acid output, non-responders to therapy, and high gastrin levels suggestive of Zollinger-Ellison syndrome.
- These tests can influence clinical management decisions.
Conclusions:
- Laboratory tests offer significant clinical value in the diagnosis and management of ulcer disease.
- Cost-benefit analysis is crucial for integrating these tests into diagnostic pathways.