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Human prostatic acid phosphatase: selected properties and practical applications
1Institute of Medical Biochemistry, Jagiellonian University, Collegium Medicum, Kraków, Poland.
Abstract:
Human prostatic acid phosphatase (EC 3.1.3.2) is a non-specific phosphomonoesterase, synthetized and secreted into seminal plasma under androgenic control. The enzyme is a dimer of molecular weight around 100 kDa. Gene coding this protein is localized on chromosome 3. Since many years prostatic phosphatase has been used as a marker of diagnosis and therapy control of cancer of the prostate gland. The biological role of this enzyme, however, remains unknown and needs further exploration.