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Sarcoid reactions in cystic duct carcinoma
M Klein1, P Kaminsky, J Deibener
1Service de Médecine J, Centre Hospitalier Universitaire de Nancy, Hôpitaux de Brabois, Vandoeuvre-lès Nancy, France.
Chest
|October 1, 1994
Abstract:
A diagnosis of sarcoidosis was evoked in a 61-year-old man on clinical and histologic bases. Nevertheless, a bile duct carcinoma was disclosed in association with the discovery of generalized sarcoid-like granulomas. This is only the third time that such an association has been described. HLA-B8, DR3, and DRw52 antigens were found, suggesting that altered immunologic mechanisms could play a role in the pathogenesis of this sarcoid-like reaction.