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Related Experiment Videos

Menopausal changes in body composition and energy expenditure

S B Heymsfield1, D Gallagher, E T Poehlman

  • 1Department of Medicine, Obesity Research Center, St. Luke's-Roosevelt Hospital Center, Columbia University, New York, New York.

Experimental Gerontology
|May 1, 1994
PubMed
Summary

Menopause and aging trigger weight gain and body composition changes in women, increasing health risks. Further research is needed to understand these shifts and develop interventions.

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Area of Science:

  • Women's health
  • Endocrinology
  • Gerontology

Background:

  • Adult women often experience weight gain with age, frequently coinciding with menopause.
  • Aging is associated with detrimental body composition changes, including fat accumulation and loss of lean mass.
  • These physiological changes during menopause and aging are linked to increased risks of chronic diseases.

Purpose of the Study:

  • To review studies on menopause and aging-related weight gain and body composition alterations in women.
  • To highlight current knowledge gaps in understanding these physiological changes.
  • To emphasize novel research methodologies for in vivo body composition and energy expenditure assessment.

Main Methods:

  • Literature review of selected studies on menopause, aging, weight gain, and body composition.

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  • Analysis of research methodologies for assessing body composition and energy expenditure.
  • Identification of areas requiring further investigation.

    • Main Results:

    • Menopause is a critical period for accelerated weight gain and adverse body composition shifts in women.
    • Age-related changes include increased body fat (especially visceral) and extracellular fluid, with decreased bone mineral and body cell mass.
    • These changes are associated with elevated risks for malignancies, cardiovascular disease, and osteoporosis.

    Conclusions:

    • Menopause significantly influences weight and body composition in aging women, impacting long-term health.
    • Further research is essential to elucidate the mechanisms behind these changes and their clinical implications.
    • Advanced in vivo research methods are crucial for a comprehensive understanding of body composition and energy expenditure.