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Phage display of a human antibody against Clostridium tetani toxin
G Esposito1, E Scarselli, C Traboni
1Istituto di Ricerche di Biologia Molecolare P. Angeletti (IRBM), Pomezia (Roma), Italy.
Gene
|October 11, 1994
Abstract:
9F12, a human antibody capable of neutralising tetanus toxin in an animal model, has been expressed as a Fab fragment in a phagemid system. The nucleotide sequence for the variable domain of both chains has been determined and compared to germline sequences.