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Adaptive classification of myocardial electrogram waveforms

W J Gibb1, D M Auslander, J C Griffin

  • 1Cardiovascular Research Institute, University of California, San Francisco 94143.

IEEE Transactions on Bio-Medical Engineering
|August 1, 1994
PubMed
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Changes in heart electrical signals can fool implantable cardioverter-defibrillators. This study introduces an adaptive method to detect these signal shape changes, improving classifier accuracy and reducing errors.

Area of Science:

  • Biomedical Engineering
  • Cardiology
  • Signal Processing

Background:

  • Myocardial electrogram complex morphology can change due to physiological and electrical transients.
  • Morphological electrogram classifiers used in implantable cardioverter-defibrillators (ICDs) may be unreliable due to these gradual shape changes.

Purpose of the Study:

  • To develop and evaluate a method for detecting gradual changes in myocardial electrogram complex shape.
  • To assess the impact of this detection method on the reliability of electrogram classifiers.

Main Methods:

  • A novel method for detecting gradual electrogram complex shape changes was developed.
  • This method was integrated into a simple adaptive classification scheme.
  • The adaptive scheme was evaluated using data from six subjects, with a focus on two exhibiting significant morphologic drift.

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Main Results:

  • Extensive morphologic drift of normal sinus beats was observed in two out of six subjects.
  • The proposed adaptive classification scheme demonstrated a reduction in classification error rates compared to non-adaptive methods.
  • The method successfully identified and adapted to gradual changes in electrogram morphology.

Conclusions:

  • Gradual changes in myocardial electrogram shape pose a challenge to existing classifiers in implantable cardioverter-defibrillators.
  • An adaptive classification scheme incorporating a novel detection method can improve the reliability of electrogram analysis.
  • This approach has the potential to enhance the performance and safety of implantable cardioverter-defibrillators.