Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Plasticity of astrocytes

Y Shao1, K D McCarthy

  • 1Department of Pharmacology, University of North Carolina at Chapel Hill 27599-7365.

Glia
|June 1, 1994
PubMed
Summary
This summary is machine-generated.

Astrocytes exhibit remarkable plasticity, altering their functions and characteristics throughout life. This adaptability is crucial for responding to changing brain environments and neuronal signals.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Association between residential greenness exposure and obesity risk based on remote sensing].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi·2026
Same author

[Analysis of the incidence and mortality trends of malignant tumors among elderly people in tumor registration areas of Yunnan Province from 2012 to 2020].

Zhonghua zhong liu za zhi [Chinese journal of oncology]·2026
Same author

[Rifampicin-resistant tuberculosis prevention and control in Jiangsu Province from 2013 to 2023].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi·2025
Same author

Current-driven nonequilibrium electrodynamics in graphene revealed by nano-infrared imaging.

Nature communications·2025
Same author

[Relapse-related candidate genes and their clinicopathological connections of diffuse large B cell lymphoma].

Zhonghua bing li xue za zhi = Chinese journal of pathology·2025
Same author

[Structural equation analysis and modeling of fect and ankles WMSDs and its adverse ergonomic factors].

Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases·2025

Area of Science:

  • Neuroscience
  • Cell Biology
  • Astrocyte Biology

Background:

  • Astrocytes perform diverse functions in the brain.
  • Astrocytes display significant phenotypic plasticity throughout life.
  • Astrocytic characteristics change in response to developmental and environmental cues.

Purpose of the Study:

  • To review examples of astrocytic plasticity.
  • To highlight the dynamic nature of astrocyte function.
  • To explore how astrocytes adjust to brain changes.

Main Methods:

  • Review of existing literature on astrocytic plasticity.
  • Analysis of changes in glial receptor expression.
  • Examination of reciprocal regulation by neurotransmitters.

Related Experiment Videos

Main Results:

  • Astrocytic recognition of neuronal signals can change quantitatively and qualitatively.
  • Adrenergic receptor expression in astrocytes is altered by neuronal degeneration.
  • Glial morphology is reciprocally regulated by neurotransmitters like norepinephrine and glutamate.

Conclusions:

  • Astrocytic plasticity is essential for adapting to brain microenvironments.
  • Changes in astrocytic receptors and morphology impact neuronal activity.
  • Reactive astrocytes up-regulate beta-adrenergic receptors during degeneration.