Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Predicting the compressive mechanical behavior of bone

T S Keller1

  • 1Department of Mechanical Engineering, University of Vermont, Burlington 05405-0156.

Journal of Biomechanics
|September 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Influence of sport on isoinertial trunk muscle performance development: a 2 years prospective study].

Revue medicale suisse·2013
Same author

Interpretation and parameterization of dynamic trunk isoinertial movements using an ensemble-averaging technique.

Clinical biomechanics (Bristol, Avon)·2013
Same author

Damage-based finite-element vertebroplasty simulations.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·2004
Same author

A predictive model for outcome after conservative decompression surgery for lumbar spinal stenosis.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·2003
Same author

Posture-dependent trunk extensor EMG activity during maximum isometrics exertions in normal male and female subjects.

Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology·2003
Same author

A prospective study on CT scan outcomes after conservative decompression surgery for lumbar spinal stenosis.

Journal of spinal disorders & techniques·2003
Same journal

Influence of iliofemoral ligament laxity on hip joint contact forces during gait.

Journal of biomechanics·2026
Same journal

Associations of sagittal spinal alignment with shear wave velocity, thickness, and echo intensity of muscles attached to the spine and pelvis in healthy women.

Journal of biomechanics·2026
Same journal

The gait lab effect: symmetry restoration strategy after anterior cruciate ligament reconstruction is different in natural environments than the gait laboratory.

Journal of biomechanics·2026
Same journal

Mediolateral trunk control, rather than temporal gait control, is associated with treadmill walking adaptation in healthy older adults.

Journal of biomechanics·2026
Same journal

Examination of participant sex bias in international society of biomechanics conference abstract submissions: patterns across cohorts, countries, and contexts.

Journal of biomechanics·2026
Same journal

Shear wave velocity of biceps femoris and medial gastrocnemius in different positions and intensities: a cross-sectional study in healthy young males.

Journal of biomechanics·2026
See all related articles

This study reveals that bone

Area of Science:

  • Biomechanical Engineering
  • Materials Science
  • Orthopedics

Background:

  • Human bone's mechanical properties vary significantly with composition.
  • Understanding these relationships is crucial for diagnosing bone conditions and developing treatments.

Purpose of the Study:

  • To determine the mathematical relationship between human bone's compressive mechanical properties and its composition.
  • To analyze how this relationship changes across different compositional ranges.

Main Methods:

  • Conducted destructive mechanical tests on 496 human bone specimens (trabecular and cortical).
  • Analyzed specimens from lumbar vertebrae and femoral sites of five male donors (ages 46-84).
  • Examined variations in strength and stiffness relative to apparent dry density, apparent ash density, and mineral content.

Related Experiment Videos

Main Results:

  • Power models showed high correlations (R2 > 0.81) between mechanical properties and bone composition.
  • Apparent ash density was the best single predictor: Strength (S) = 117 (apparent ash density)^1.93 and Stiffness (E) = 10.5 (apparent ash density)^2.57.
  • The exponents in power models varied with density, indicating a non-linear dependency.

Conclusions:

  • The mathematical relationship between bone's mechanical properties and composition is highly dependent on the density and mineral content range studied.
  • Power functions, particularly using apparent ash density, accurately predict bone strength and stiffness.
  • Different density ranges exhibit distinct mathematical dependencies, with higher densities showing exponents greater than two.