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[A case report: sepsis associated with hypoglycemia]

A Suzuki1, M Uno, K Arima

  • 1Department of Internal Medicine and Pathology, Kawasaki Municipal Hospital.

Kansenshogaku Zasshi. the Journal of the Japanese Association for Infectious Diseases
|August 1, 1994
PubMed
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This case report details a fatal sepsis case in a woman with uterus carcinoma, complicated by severe hypoglycemia. It highlights a rare presentation of sepsis, emphasizing the critical link between infection and blood sugar levels.

Area of Science:

  • Internal Medicine
  • Infectious Diseases
  • Oncology

Background:

  • A 78-year-old female with a history of uterus carcinoma and radiotherapy presented with altered consciousness.
  • She had a prior diagnosis of uterus carcinoma, treated with radiotherapy a year before admission.

Observation:

  • On admission, the patient exhibited hypothermia (35.5°C), severe hypotension (50 mmHg systolic), ascites, and a semicomatose state.
  • Laboratory results revealed marked leukocytosis (38,800/microliters), profound hypoglycemia (3 mg/dL), and severe metabolic acidosis (pH 6.9).

Findings:

  • The patient rapidly deteriorated and expired within 10 hours despite aggressive treatment with catecholamines and antibiotics.
  • Blood cultures identified Bacteroides ovatus, and autopsy confirmed uterine abscess and perforation, alongside liver cirrhosis.

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Implications:

  • This case represents a rare instance of sepsis complicated by severe hypoglycemia, a clinical manifestation rarely documented.
  • It underscores the importance of considering and managing hypoglycemia in patients with sepsis, particularly those with a history of malignancy.