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Published on: January 28, 2012
Antidepressant augmentation with lithium
1University of Tennessee/Baptist Healthplex Family Practice Residency Program, Memphis.
Abstract:
Depression is one of the most prevalent disorders seen in primary care. About 50% of depression is treated in general medical settings. Although depression is highly treatable, incomplete response to a single antidepressant is common. We describe two clinical cases in which antidepressant augmentation was a therapeutic option and lithium carbonate was an appropriate choice. A brief review of the practical aspects of the clinical pharmacology of lithium is included. Lithium is a well-tolerated, safe, and effective medication for antidepressant augmentation.
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