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Identification of human monoamine oxidase (MAO) A and B gene promoters
1Department of Molecular Pharmacology and Toxicology, School of Pharmacy, University of Southern California, Los Angeles.
Journal of Neural Transmission. Supplementum
|January 1, 1994
Abstract:
The promoter of human monoamine oxidase (MAO) A and B genes have been identified. The core promoter region of MAO A is comprised of two 90 bp repeats each of which contains two Sp1 elements and lacks a TATA box. The MAO B core promoter region contains two sets of overlapping Sp1 sites which flank a CACCC element all upstream of a TATA box. The different organization of the MAO A and B promoters may underlie their different cell and tissue specific expression.