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Alkaloids from Lycopodium casuarinoides
1Institute of Marine Resources, National Sun Yat-sen University, Kaohsiung, Taiwan, Republic of China.
Journal of Natural Products
|June 1, 1994
Abstract:
In addition to huperzinine [1], a new alkaloid, N-demethylhuperzinine [2], was isolated from the aerial parts of Lycopodium casuarinoides by bioassay-directed fractionation. The structure of 2 was established by spectral analysis and extensive nOe difference nmr studies as well as spectral comparison with huperzinine. N-Demethylhuperzinine [2] exhibited anticholinesterase activity in pharmacological studies.