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[Effect of hyperbaric oxygen on aerobic bacteria]
Zeitschrift Fur Experimentelle Chirurgie
|January 1, 1976
Summary
Hyperbaric oxygen therapy inhibited the growth of 8 pathogenic aerobic bacteria species. This suggests its potential benefit for treating superficial pyogenic infections associated with vascular diseases.
Area of Science:
- Microbiology
- Hyperbaric Medicine
- Bacteriology
Background:
- Pathogenic aerobic bacteria are a common cause of superficial infections.
- Obliterating vascular diseases can predispose individuals to such infections.
- Hyperbaric oxygen therapy is a medical treatment involving breathing oxygen in a pressurized environment.
Purpose of the Study:
- To investigate the in vitro effect of hyperbaric oxygen on the growth of pathogenic aerobic bacteria.
- To determine the potential of hyperbaric oxygen therapy for treating pyogenic infections in patients with vascular diseases.
Main Methods:
- Eight species of pathogenic aerobic bacteria were cultured.
- Bacterial cultures were exposed to hyperbaric oxygen (3 atmospheres absolute) for 2-hour intervals, three times within 24 hours at 37°C.
- The inhibitory effect of oxygen was quantified using a densitometric method.
Main Results:
- Hyperbaric oxygen demonstrated an inhibitory effect on the growth of all 8 tested bacterial species.
- The percentage of growth inhibition was assessed in fluid cultures and compared to controls.
Conclusions:
- Hyperbaric oxygen treatment exhibits antimicrobial properties against pathogenic aerobic bacteria.
- The findings support the clinical consideration of hyperbaric oxygen therapy for superficial pyogenic conditions linked to obliterating vascular diseases.