Synthesis of new acyclic pyrimidine nucleoside analogs as potential antiviral drugs

Possible involvement of an acylation mechanism in thalidomide-induced teratogenesis of the newt (Pleurodeles waltl.).

Development, growth & differentiation·2023

New Class of 5-Lipoxygenase Inhibitors: Correlation Between Inhibition of LTB4 Production and Chemiluminescence of Human Polymorphonuclear Granulocytes.

Pharmaceutical research·2013

Enzyme replacement therapy with alglucosidase alfa in 44 patients with late-onset glycogen storage disease type 2: 12-month results of an observational clinical trial.

Journal of neurology·2009

[Polymyositis associated with thymoma].

Der Nervenarzt·2009

Bronchial epithelial cells cultured from clinically stable lung allograft patients promote the development of macrophages from monocytes rather than dendritic cells.

Thorax·2009

Distinct muscle imaging patterns in myofibrillar myopathies.

Neurology·2008

Structural and Mechanistic Studies of ADEPs Yield Potent Antibacterials and a Drug Formulation Strategy for Tuberculosis.

Journal of medicinal chemistry·2026

A 177Lu-Labeled Circular Bivalent Aptamer for PTK7-Targeting Radionuclide Therapy in Ovarian Cancer and Orthotopic Hepatoblastoma.

Journal of medicinal chemistry·2026

From Fragment Hit to Clinical Candidate: Discovery of Dual H1R/H4R Ligands with Superior Efficacy in Allergic Conjunctivitis.

Journal of medicinal chemistry·2026

Potent Anticancer Tethered Organorhodium(III) Complexes Target the Mitochondria.

Journal of medicinal chemistry·2026

Discovery of a Covalent NLRP3 LRR-Domain Probe: Reversing Renal Fibrosis via Immunometabolic Reprogramming in Organoid and Murine Models.

Journal of medicinal chemistry·2026

Lead Optimization of Multimutant KRAS Switch-II Pocket Macrocyclic Inhibitors via Isosteric Replacement to Improve ADME and Oral Exposure.

Journal of medicinal chemistry·2026

European Bioanalysis Forum cross-industry perspective on emerging small-molecule modalities: bioanalytical challenges and potential mitigation strategies.

Bioanalysis·2026

Cannabidiol (CBD) for Pain: A Narrative Review of Evidence to Date.

Cureus·2026

Natural Deep Eutectic Solvent for Extracting Antioxidants From Spent Coffee Grounds and Improving Stability of Chlorogenic Acid Against Heat and Light Stress.

Journal of food science·2026

Cannabidiol's prosexual effects in sexually active and sexually inhibited male rats.

Neuroscience·2026

The Association Between New Zealand Blackcurrant Anthocyanins and Airway Inflammation, Including PAI-1, in Asthma: A Placebo-Controlled Crossover Feasibility Study.

Respiratory medicine·2026

Design, synthesis, anti-oomycete, anti-fungal, and nematicidal activities of novel eugenol acyloxy/sulfonyloxy derivatives containing an isoxazoline ring.

Bioorganic chemistry·2026

Related Experiment Videos

Synthesis of new acyclic pyrimidine nucleoside analogs as potential antiviral drugs

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Possible involvement of an acylation mechanism in thalidomide-induced teratogenesis of the newt (Pleurodeles waltl.).

New Class of 5-Lipoxygenase Inhibitors: Correlation Between Inhibition of LTB4 Production and Chemiluminescence of Human Polymorphonuclear Granulocytes.

Enzyme replacement therapy with alglucosidase alfa in 44 patients with late-onset glycogen storage disease type 2: 12-month results of an observational clinical trial.

[Polymyositis associated with thymoma].

Bronchial epithelial cells cultured from clinically stable lung allograft patients promote the development of macrophages from monocytes rather than dendritic cells.

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Structural and Mechanistic Studies of ADEPs Yield Potent Antibacterials and a Drug Formulation Strategy for Tuberculosis.

A 177Lu-Labeled Circular Bivalent Aptamer for PTK7-Targeting Radionuclide Therapy in Ovarian Cancer and Orthotopic Hepatoblastoma.

From Fragment Hit to Clinical Candidate: Discovery of Dual H1R/H4R Ligands with Superior Efficacy in Allergic Conjunctivitis.

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Lead Optimization of Multimutant KRAS Switch-II Pocket Macrocyclic Inhibitors via Isosteric Replacement to Improve ADME and Oral Exposure.

European Bioanalysis Forum cross-industry perspective on emerging small-molecule modalities: bioanalytical challenges and potential mitigation strategies.

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Cannabidiol's prosexual effects in sexually active and sexually inhibited male rats.

The Association Between New Zealand Blackcurrant Anthocyanins and Airway Inflammation, Including PAI-1, in Asthma: A Placebo-Controlled Crossover Feasibility Study.

Design, synthesis, anti-oomycete, anti-fungal, and nematicidal activities of novel eugenol acyloxy/sulfonyloxy derivatives containing an isoxazoline ring.

Related Experiment Videos

Synthesis of new acyclic pyrimidine nucleoside analogs as potential antiviral drugs

Abstract:

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