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Meta-analysis of the literature: guideline development for prostate cancer treatment. American Urological Association
M S Austenfeld1, I M Thompson, R G Middleton
1Section of Urology, University of Kansas Medical Center, Kansas City.
Abstract:
Medical interventions are identified to be in need of practice guidelines based on several criteria, including uncertainty of therapeutic benefit, economic impact, variation in practice patterns and lack of objective data for new developments. Treatment of localized adenocarcinoma of the prostate meets these criteria and has been identified as an issue in need of practice guideline development. The American Urological Association began working toward establishing prostate cancer treatment guidelines in 1989. An explicit method based on collection of scientific data was adopted, which requires complete review of the literature and analysis of the evidence collected. An update on the progress toward this data analysis and guideline document is presented.
Insights
Practice guidelines are needed for medical interventions like prostate cancer treatment due to uncertainties and varied practices. The American Urological Association is developing evidence-based guidelines for localized adenocarcinoma of the prostate.
Area of Science:
- Urology
- Medical Guidelines
- Oncology
Background:
- Medical interventions often require practice guidelines due to factors like uncertain benefits, economic impact, practice variations, and limited data.
- Localized adenocarcinoma of the prostate treatment exemplifies these criteria, highlighting the need for established guidelines.
Purpose of the Study:
- To provide an update on the development of practice guidelines for the treatment of localized prostate cancer.
- To outline the methodology for creating evidence-based guidelines for prostate cancer treatment.
Main Methods:
- Adoption of an explicit methodology for guideline development.
- Systematic collection and comprehensive review of scientific literature.
- Analysis of collected evidence to inform guideline recommendations.
Main Results:
- The American Urological Association initiated prostate cancer treatment guideline development in 1989.
- Progress has been made in the data analysis phase for the guideline document.
Conclusions:
- Developing evidence-based practice guidelines for localized prostate cancer is crucial.
- The ongoing systematic review and data analysis are essential steps toward guideline finalization.