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[The effects of hypertonic lactated Ringer's solution during transurethral surgery]
Masui. the Japanese Journal of Anesthesiology
|August 1, 1994
Summary
Hypertonic lactated Ringer's solution (HLS) prevents dangerous drops in sodium and osmolarity during transurethral resection of the prostate (TUR-P). This essential fluid therapy helps maintain patient stability during the procedure.
Area of Science:
- Anesthesiology
- Nephrology
- Urology
Background:
- Transurethral resection of the prostate (TUR-P) can lead to fluid shifts and electrolyte imbalances.
- Intraoperative fluid management is critical for patient safety during TUR-P.
Purpose of the Study:
- To evaluate the efficacy of hypertonic lactated Ringer's solution (HLS) in preventing hyponatremia and hypoosmolarity during TUR-P.
- To compare the effects of HLS versus regular lactated Ringer's solution on plasma sodium and osmolarity levels.
Main Methods:
- A comparative study involving two groups of patients undergoing TUR-P (n=7 each).
- One group received HLS (213 mEq.l-1 sodium), while the control group received regular lactated Ringer's solution.
- Plasma sodium, osmolarity, and serum ADH levels were monitored.
Main Results:
- Patients receiving regular lactated Ringer's solution showed significant decreases in plasma sodium and osmolarity.
- No significant changes in plasma sodium or osmolarity were observed in the HLS group.
- Serum ADH levels increased significantly in the HLS group post-administration, suggesting a response to increased sodium concentration.
Conclusions:
- HLS effectively prevents hyponatremia and hypoosmolarity in patients undergoing TUR-P.
- HLS is a suitable and potentially essential fluid therapy for routine use during TUR-P procedures.