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Age-related decrease in the naive (OX22+) T cells in F344 rats
1GRECC (182), Audie L. Murphy Memorial Veterans Hospital, San Antonio, Texas 78284.
Mechanisms of Ageing and Development
|June 1, 1994
Abstract:
The frequency of the cells bearing the naive marker (OX22+) in T cells, helper, and cytotoxic/suppressor T cell subsets isolated from the spleens of young and old F344 rats were measured by flow cytometry. The percentage of naive cells in T cells decreased significantly with age and this decline occurred primarily in the helper subset.