Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Variation in glucose tolerance with ambient temperature

M I Schmidt1, M C Matos, L Branchtein

  • 1Department of Social Medicine, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.

Lancet (London, England)
|October 15, 1994
PubMed
Summary

Ambient temperature significantly impacts glucose tolerance test results. Warmer conditions show higher glucose levels and increased abnormal test occurrences, suggesting a need for temperature standardization in testing.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Difference in the prevalence of hypertension when measured according to the American Heart Association and the European Society of Cardiology hypertension cut-offs in the ELSA-Brasil cohort.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica·2025
Same author

Association between perceived stress and health-risk behaviours in workers.

Psychology, health & medicine·2020
Same author

Association between cognitive performance and self-reported glaucoma in middle-aged and older adults: a cross-sectional analysis of ELSA-Brasil.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas·2020
Same author

Neck and waist circumference values according to sex, age, and body-mass index: Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas·2020
Same author

Expanding Primary Care Access: A Telehealth Success Story.

Annals of family medicine·2017
Same author

Weight gain adequacy and pregnancy outcomes in gestational diabetes: a meta-analysis.

Obesity reviews : an official journal of the International Association for the Study of Obesity·2017

Area of Science:

  • Endocrinology
  • Clinical Chemistry
  • Metabolic Health

Background:

  • Glucose tolerance tests are crucial for diagnosing diabetes and metabolic disorders.
  • Standardized testing conditions are assumed for accurate interpretation of glucose tolerance test results.

Purpose of the Study:

  • To investigate the influence of ambient temperature on venous glucose concentrations during standardized 75 g oral glucose tolerance tests (OGTT).
  • To assess the impact of temperature variations on the diagnostic accuracy and interpretation of OGTT results.

Main Methods:

  • Analysis of 1030 standardized 75 g oral glucose tolerance tests.
  • Comparison of glucose concentrations and diagnostic outcomes between lower (5-14°C) and higher (25-31°C) ambient temperature conditions.

Related Experiment Videos

Main Results:

  • No significant difference in mean fasting glucose levels was observed across temperatures.
  • Adjusted mean 2-hour glucose concentrations were significantly lower (1.03 mmol/L) at lower ambient temperatures compared to higher temperatures (p < 0.001).
  • The incidence of abnormal glucose tolerance doubled on warmer days, indicating temperature-associated diagnostic variation.

Conclusions:

  • Ambient temperature exhibits a clinically significant effect on venous glucose concentrations and diagnostic accuracy during oral glucose tolerance testing.
  • Findings suggest a need for temperature standardization during OGTT or the development of alternative diagnostic strategies for variable temperature environments.