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Related Experiment Videos

Endoscopic laser excisional biopsy for selected glottic carcinomas

G Peretti1, J Cappiello, P Nicolai

  • 1Department of Otorhinolaryngology, University of Brescia, Italy.

The Laryngoscope
|October 1, 1994
PubMed
Summary

Carbon dioxide laser excision effectively treats early vocal cord squamous cell carcinomas (SCCs). This minimally invasive approach offers a high cure rate, serving as a viable alternative to traditional treatments for selected patients.

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Corrigendum to "How reliable is assessment of true vocal cord-arytenoid unit mobility in patients affected by laryngeal cancer? a multi-institutional study on 366 patients from the ARYFIX collaborative group" [Oral Oncol. 152C (2024) 106744].

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Area of Science:

  • Otolaryngology
  • Oncology
  • Surgical Innovation

Background:

  • Squamous cell carcinoma (SCC) of the true vocal cord requires effective treatment strategies.
  • Traditional treatments include radiotherapy and open neck surgery, each with potential side effects.

Purpose of the Study:

  • To evaluate the efficacy and outcomes of carbon dioxide laser excision for early-stage vocal cord SCC.
  • To assess the feasibility of endoscopic excisional biopsy as a primary treatment modality.

Main Methods:

  • Retrospective analysis of 44 previously untreated patients with true vocal cord SCC (Tis and T1a stages).
  • Patients underwent carbon dioxide laser excision between January 1988 and December 1990.
  • Follow-up averaged 28 months, with analysis of recurrence and re-treatment outcomes.

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Main Results:

  • A definitive cure rate of 94.7% was achieved in 38 patients treated with laser excision alone.
  • Recurrence occurred in 8 (18%) patients, managed with various re-treatment options.
  • Endoscopic laser treatment demonstrated a high success rate for selected glottic SCC cases.

Conclusions:

  • Carbon dioxide laser excision is an excellent alternative treatment for selected early-stage glottic squamous cell carcinomas.
  • Endoscopic management offers a minimally invasive option with high cure rates, potentially avoiding radiotherapy or open surgery.