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Obstructive bronchial aspergillosis after heart transplantation
M Hummel1, S Schüler, S Hempel
1Division of Thoracic and Cardiovascular Surgery, German Heart Institute Berlin.
Mycoses
|November 1, 1993
Summary
Obstructive bronchial aspergillosis, a rare Aspergillus infection, can affect patients with acquired immunodeficiency syndrome (AIDS) or after heart transplantation (HTx) due to T-cell reduction. Early antifungal therapy is crucial to prevent invasive disease progression.
Area of Science:
- Medical Mycology
- Immunocompromised Hosts
Background:
- Obstructive bronchial aspergillosis is a rare complication of Aspergillus infection.
- It affects patients with acquired immunodeficiency syndrome (AIDS) and those post-heart transplantation (HTx) with significant T-cell reduction from antithymocyte globulin (ATG) and corticosteroids.
- Unlike invasive forms, it may present asymptomatically, lacking typical signs like inflammation or infiltrates.