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Altered reticuloendothelial function in long-term renal allograft recipients
Archives of Surgery (Chicago, Ill. : 1960)
|December 1, 1976
Summary
Reticuloendothelial system (RES) phagocytic function is defective in 70% of long-term renal transplant patients, linked to steroid dosage and infection risk. This study did not find evidence of cytomegalovirus-induced immunosuppression.
Area of Science:
- Immunology
- Nephrology
- Hepatology
Background:
- Long-term renal allograft recipients may experience altered immune function.
- Reticuloendothelial system (RES) plays a crucial role in immune surveillance and clearance.
- Assessing RES phagocytic function is important for understanding post-transplant immunity.