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Related Experiment Videos

Headache in stroke: the Copenhagen Stroke Study

H S Jørgensen1, H F Jespersen, H Nakayama

  • 1Department of Neurology, Bispebjerg Hospital, Copenhagen, Denmark.

Neurology
|October 1, 1994
PubMed
Summary
This summary is machine-generated.

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Aphasia in acute stroke: incidence, determinants, and recovery.

Annals of neurology·1995

Headache after stroke is linked to age and sex, and more common in vertebrobasilar strokes. This study found no association between stroke-related headache and stroke severity or outcome.

Area of Science:

  • Neurology
  • Stroke Medicine
  • Headache Research

Background:

  • Uncertainty surrounds the incidence, pathophysiology, risk factors, and outcomes of stroke-related headaches.
  • Previous research has not clearly defined the relationship between headache and stroke severity or prognosis.

Purpose of the Study:

  • To investigate the incidence and independent risk factors of headache in acute stroke patients.
  • To determine the association between stroke-related headache and stroke severity, lesion characteristics, and clinical outcomes.

Main Methods:

  • A prospective, community-based study of 1,128 consecutive acute stroke patients was conducted.
  • 867 patients (77%) were able to communicate and assess stroke severity using the Scandinavian Stroke Scale (SSS).
  • Multivariate regression analyses were employed to identify independent risk factors and associations.

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Main Results:

  • Headache occurred in 28% of patients. Independent risk factors included older age, female sex, intracerebral hemorrhage, vertebrobasilar stroke, and ischemic heart disease.
  • Headache lateralization was ipsilateral to the lesion in 68% of cases.
  • No correlation was found between headache and initial stroke severity (SSS), lesion size, cortical involvement on CT, stroke outcome (SSS), or mortality.

Conclusions:

  • Stroke-related headache is associated with demographic factors (age, sex) and stroke type (vertebrobasilar territory).
  • Headache is not linked to stroke severity or cortical involvement in patients who can report reliably.
  • Stroke-related headache does not appear to be related to stroke outcome or mortality.