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[The nervous system in rheumatic diseases]

Y T Konttinen1, S Santavirta

  • 1Anatomiska Institutionen, Forkningsenheten vid Invalidstiftelsen, Helsingfors universitetscentralsjukhus.

Nordisk Medicin
|January 1, 1994
PubMed
Summary

Pain in rheumatic diseases stems from complex interactions between body tissues, the extracellular matrix, and the nervous system, alongside neural changes. This review explores these factors and their impact on treatment strategies.

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Area of Science:

  • Rheumatology
  • Neuroscience
  • Cell Biology

Context:

  • Rheumatic diseases involve complex pain mechanisms.
  • Understanding pain pathways is crucial for effective treatment.
  • Interactions between multiple biological systems contribute to pain perception.

Purpose:

  • To review the interactive effects contributing to pain in rheumatic diseases.
  • To explore the role of tissue, extracellular, and nervous system interactions.
  • To examine how these phenomena influence treatment approaches.

Summary:

  • Pain in rheumatic diseases arises from intricate interplay between tissues, the extracellular environment, and the nervous system.
  • Alterations within the nervous system and nerve cell properties are key factors.
  • The review synthesizes these complex interactions and their clinical implications.

Impact:

  • Provides a comprehensive overview of pain mechanisms in rheumatic diseases.
  • Highlights the importance of a multi-system approach to pain management.
  • Informs future research and therapeutic strategies for rheumatic disease pain.

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