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Successful physostigmine treatment of acute dothiepin intoxication
1Drug Information Center, ABDA, Eschborn.
Die Pharmazie
|August 1, 1994
Abstract:
We report on a severe intoxication with the tricyclic antidepressant dothiepin. A treatment with a continuous infusion of physostigmine was successful and improved the ventricular arrhythmia. Dothiepin and its active metabolites were determined in plasma and urine by HPLC.