[Anemia and thrombocytopenia in malaria. I. Mechanisms]
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J Górski1, W Nahorski, J Goljan
1Kliniki Chorób Zawodowych i Tropikalnych Instytutu Medycyny Morskiej i Tropikalnej, Gdyni.
Pathomechanism of thrombocytopenia and anaemia which frequently occur in patients with malaria is of a complex origin. Anaemia occurs due to sequestrating, destruction and hemolysis of damaged, parasite infected erythrocytes, as well as of the impaired and ineffective erythropoiesis in the marrow. Thrombocytopenia in these patients may also result from both increased destruction of blood platelets and decreased thrombocytopoiesis. Similar natures of the processes cause that anaemia and thrombocytopenia frequently co-exist in patients with malaria.
Pathomechanism of thrombocytopenia and anaemia which frequently occur in patients with malaria is of a complex origin. Anaemia occurs due to sequestrating, destruction and hemolysis of damaged, parasite infected erythrocytes, as well as of the impaired and ineffective erythropoiesis in the marrow. Thrombocytopenia in these patients may also result from both increased destruction of blood platelets and decreased thrombocytopoiesis. Similar natures of the processes cause that anaemia and thrombocytopenia frequently co-exist in patients with malaria.