Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Characterization, standardization and experiences with KONE ISE for Mg2+

A Lewenstam1, N Blomqvist, J Ost

  • 1Laboratory of Analytical Chemistry, Abo Akademi University, Turku-Abo, Finland.

Scandinavian Journal of Clinical and Laboratory Investigation. Supplementum
|January 1, 1994
PubMed
Summary

This study presents a new automated method for measuring ionized magnesium in human blood serum using a magnesium-selective electrode. This advancement allows for precise determination of biologically active magnesium levels in patients.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Modeling potentiometric sensitivity of conducting polymers.

Analytical chemistry·2011
Same author

Validation of the Mini-TQ in a Dutch-speaking population: a rapid assessment for tinnitus-related distress.

B-ENT·2011
Same author

Burst transcranial magnetic stimulation: which tinnitus characteristics influence the amount of transient tinnitus suppression?

European journal of neurology·2010
Same author

A small modification to a decompressive craniotomy to improve the brain-cranium interface: technical note.

Minimally invasive neurosurgery : MIN·2009
Same author

Carbonate ion selective electrodes with trifluoroacetophenone derivatives in potentiometric clinical analyser.

Talanta·2008
Same author

Interferences in a polypyrrole-based amperometric ammonia sensor.

Talanta·2008

Area of Science:

  • Clinical Chemistry
  • Analytical Chemistry
  • Biomedical Engineering

Background:

  • Ionized magnesium is the biologically active form.
  • Accurate measurement of ionized magnesium is crucial for patient diagnosis.
  • Existing methods for magnesium determination may not fully capture the ionized fraction.

Purpose of the Study:

  • To present the principles of a fully automated potentiometric determination of ionized magnesium in human blood serum.
  • To evaluate the analytical performance of a novel measurement system.
  • To discuss the clinical significance of measuring ionized magnesium.

Main Methods:

  • Incorporation of a magnesium-selective electrode into a commercial six-channel electrolyte analyzer (Microlyte 6).
  • Development of a fully automated potentiometric assay for ionized magnesium.

Related Experiment Videos

  • Validation of the system using real patient samples.

    • Main Results:

    • Successful implementation of an automated system for ionized magnesium determination.
    • Demonstration of the system's analytical performance.
    • Presentation of results from real patient samples.

    Conclusions:

    • The developed system enables reliable, automated measurement of ionized magnesium in human blood serum.
    • This method provides a valuable tool for assessing the biologically active magnesium fraction.
    • The significance of ionized magnesium as a clinical parameter is highlighted.