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Chordal tissue in endomyocardial biopsies
L Wiklund1, M B Suurküla, C Kjellström
1Department of Cardiothoracic Surgery, Sahlgrenska Hospital, University of Gothenburg, Sweden.
Scandinavian Journal of Thoracic and Cardiovascular Surgery
|January 1, 1994
Summary
Chordal tissue in heart biopsies is uncommon and does not typically cause tricuspid valve dysfunction in heart transplant recipients. This finding suggests the tricuspid valve is not significantly harmed by occasional chordal tissue capture during biopsy.
Area of Science:
- Cardiology
- Transplant Medicine
- Pathology
Background:
- Endomyocardial biopsies are crucial for monitoring heart transplant rejection.
- Tricuspid valve integrity is vital for cardiac function post-transplant.
- Chordal tissue presence in biopsies raises concerns about potential valvular damage.
Purpose of the Study:
- To investigate the incidence of chordal tissue in heart transplant biopsies.
- To determine if chordal tissue presence correlates with tricuspid regurgitation or abnormalities.
- To assess the impact of chordal tissue capture on tricuspid valve function.
Main Methods:
- Prospective investigation of endomyocardial biopsies in heart transplant recipients.
- Histological analysis to detect chordal tissue in biopsy samples.
- Postoperative echocardiography and Doppler studies to evaluate tricuspid valve function.
Main Results:
- Chordal tissue was detected in 24 of 1,265 biopsy samples (206 patients).
- No significant increase in tricuspid regurgitation or major valvular abnormalities observed.
- Occasional chordal tissue capture did not lead to tricuspid valve dysfunction.
Conclusions:
- The incidence of chordal tissue in heart transplant biopsies is low.
- Biopsy-related chordal tissue capture does not typically result in adverse tricuspid valve outcomes.
- The tricuspid valve appears resilient to incidental chordal tissue involvement during endomyocardial biopsy.