Related Experiment Video
Updated: Sep 11, 2026

Echocardiographic Assessment of Cardiac Anatomy and Function in Adult Rats
Published on: December 13, 2019
[Heart defects in rheumatoid arthritis patients (the results of a multiyear prospective clinico-echocardiographic
Insights
Rheumatoid arthritis patients have a 7.9% risk of developing valvular heart disease, often diagnosed via echocardiography. Early detection and consistent antirheumatic therapy are crucial for managing this complication in rheumatoid arthritis (RA) patients.
Area of Science:
- Cardiology
- Rheumatology
- Clinical Medicine
Background:
- Rheumatoid arthritis (RA) is a chronic inflammatory disease.
- Valvular heart disease (VHD) is a potential complication.
- Long-term monitoring of RA patients is essential.
Purpose of the Study:
- To analyze the lifetime diagnosis of VHD in RA patients.
- To determine the incidence and types of VHD in RA.
- To evaluate the role of echocardiography in early VHD diagnosis.
Main Methods:
- Long-term clinico-echocardiographic investigation.
- Follow-up of 214 RA patients over 18 years.
- Diagnosis and classification of valvular heart lesions.
Main Results:
- VHD was detected in 7.9% (17/214) of RA patients.
- Most VHD diagnoses occurred after RA diagnosis.
- Common VHD types included mitral stenosis, aortic stenosis, and valve incompetence.
Conclusions:
- VHD is a significant concern in RA, particularly in progressive, seropositive cases.
- Prospective echocardiographic screening aids early VHD diagnosis in RA patients.
- Continuous antirheumatic therapy is vital to prevent VHD progression in RA.
Abstract:
The analysis of life-time diagnosis of valvular heart disease in rheumatoid arthritis (RA) patients has been made basing on a long-term clinico-echocardiographic investigation. Within 18-year follow-up valvular disease was revealed in 17 out of 214 RA patients (7.9%). Only 3 patients developed the disease in childhood prior to RA diagnosis. In 8 patients the diagnosis of valvular disease was established in the presence of RA, in 6 RA patients the disease was determined during the follow-up period. Mitral stenosis, aortal stenosis, combined mitral valve incompetence, combined aortal defect, mitral defect and tricuspid incompetence, combined mitral defect and pulmonary artery valvular incompetence were detected in 2, 2, 3, 1, 1, and 1 patients, respectively. Valvular disease occurs more frequently in progredient seropositive RA uncontrollable by on-going therapy. The authors emphasize the value of a prospective clinical echocardiographic examination of RA patients in early diagnosis of valvular disease in them. Frequent valvular lesions in RA patients dictate the need of persistent antirheumatic therapy to inhibit the activity and prevent progression of the disease.
More Related Videos
07:38Comprehensive Echocardiographic Assessment of Right Ventricle Function in a Rat Model of Pulmonary Arterial Hypertension
Published on: January 20, 2023
06:31Erosion Identification in Metacarpophalangeal Joints in Rheumatoid Arthritis using High-Resolution Peripheral Quantitative Computed Tomography
Published on: October 6, 2023
Related Concept Videos
Imaging Studies for Cardiovascular System I:Echocardiography
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion, evaluates...
Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Rheumatic Heart Disease I: Introduction
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
Rheumatic Heart Disease III: Medical Management
Rheumatic Heart Disease IV: Nursing Management