Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Ergospirometry in sarcoidosis patients]

M Schwaiblmair1, R Hettich, G Fruhmann

  • 1Medizinische Klinik I, Ludwig-Maximilians-Universität München.

Zeitschrift Fur Kardiologie
|January 1, 1994
PubMed
Summary

Cardiopulmonary exercise testing (CPX) provides crucial insights into pulmonary sarcoidosis, detecting early gas exchange abnormalities before resting lung function tests. CPX aids in monitoring steroid therapy effectiveness and differentiating disease stages.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The association of the N-terminal pro-brain-type natriuretic peptide response to exercise with disease severity in therapy-naive pulmonary arterial hypertension: a cohort study.

Respiratory research·2018
Same author

The association of N-terminal pro-brain-type natriuretic peptide with hemodynamics and functional capacity in therapy-naive precapillary pulmonary hypertension: results from a cohort study.

BMC pulmonary medicine·2017
Same author

[Risk stratification and follow-up assessment of patients with pulmonary arterial hypertension: Recommendations of the Cologne Consensus Conference 2016].

Deutsche medizinische Wochenschrift (1946)·2016
Same author

Obstructive sleep apnea might trigger acute pulmonary embolism: results from a cohort study.

Clinical research in cardiology : official journal of the German Cardiac Society·2016
Same author

TIDILAP: Treatment of iron deficiency in lipoprotein apheresis patients --A prospective observational multi-center cohort study comparing efficacy, safety and tolerability of ferric gluconate with ferric carboxymaltose.

Atherosclerosis. Supplements·2015
Same author

Structural Characterization of Normal and Modified Oligonucleotides by Matrix-assisted Laser Desorption Fourier Transform Mass Spectrometry.

Journal of the American Society for Mass Spectrometry·2013

Area of Science:

  • Pulmonology
  • Exercise Physiology

Context:

  • Pulmonary sarcoidosis is a complex granulomatous disease affecting the lungs.
  • Assessing disease severity and treatment response in sarcoidosis remains challenging.

Purpose:

  • To evaluate the clinical utility of cardiopulmonary exercise testing (CPX) in patients with pulmonary sarcoidosis.
  • To correlate lung function, gas exchange, and radiological findings during exercise.

Summary:

  • Cardiopulmonary exercise testing (CPX) revealed significant correlations between lung volumes and exercise parameters in 47 pulmonary sarcoidosis patients.
  • Increased relative minute ventilation and alveolar-arterial oxygen difference during exercise objectively differentiated radiological stages I and II.
  • CPX detected early gas exchange abnormalities, preceding resting lung function changes, and demonstrated steroid therapy's positive impact on ventilation and V/Q matching.

Impact:

  • CPX offers valuable additional information for assessing pulmonary sarcoidosis pathophysiology and disease progression.
  • This testing modality aids in the objective monitoring of steroid therapy efficacy.
  • CPX can identify subclinical gas exchange impairments, guiding earlier clinical management.

Related Experiment Videos