Malignant transformation of benign mesenteric cyst

Area of Science:

• Gastroenterology
• Surgical Oncology
• Pathology

Background:

• Mesenteric cysts are rare intra-abdominal masses with poorly understood etiologies and classifications.
• Complete histopathological evaluation is often challenging for accurate diagnosis.

Observation:

• A case of mesenteric cyst initially treated with incomplete excision.
• The cyst recurred over several years, exhibiting progressive growth.
• The recurrent lesion ultimately transformed into adenocarcinoma.

Findings:

• This is the first documented instance of a benign mesenteric cyst undergoing malignant transformation to adenocarcinoma.
• Incomplete excision is associated with a risk of recurrence and subsequent malignant change.

Implications:

• Complete surgical excision of all mesenteric cysts is recommended to prevent recurrence.
• Early and complete intervention may mitigate the risk of malignant transformation in mesenteric cysts.