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Acute interstitial nephritis with renal failure associated with propylthiouracil therapy
S C Reinhart1, A M Moses, L Cleary
1Department of Medicine, State University of New York (SUNY) Health Science Center at Syracuse 13210.
Abstract:
Propylthiouracil therapy is associated with a variety of adverse reactions. Renal involvement, although rare, has occurred, but neither acute interstitial nephritis nor severe acute renal failure has been reported previously. We report a case of fulminant acute interstitial nephritis with renal failure following treatment with propylthiouracil.