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Related Experiment Videos

Obesity, pregnancy, and left ventricular functioning during the third trimester

J C Veille1, R Hanson

  • 1Department of Obstetrics and Gynecology, Bowman Gray School of Medicine, Winston-Salem, NC 27157-1066.

American Journal of Obstetrics and Gynecology
|October 1, 1994
PubMed
Summary
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Obese pregnant women show similar left ventricular size and function to non-obese women. However, obese patients exhibit significant left ventricular hypertrophy, suggesting cardiac remodeling during pregnancy.

Area of Science:

  • Cardiology
  • Obstetrics
  • Physiology

Background:

  • Maternal obesity is a growing concern in pregnancy.
  • Understanding its impact on cardiovascular adaptation is crucial.

Purpose of the Study:

  • To assess left ventricular (LV) size and function in obese pregnant patients during the third trimester.
  • To compare these parameters with a control group of non-obese pregnant women.

Main Methods:

  • M-mode echocardiography was performed on eight morbidly obese pregnant patients.
  • A control group of 36 normal pregnant patients was included.
  • Patients with hypertension or diabetes were excluded.

Main Results:

  • No significant differences were observed in LV end-diastolic dimension, fractional shortening, or cardiac index between groups.

Related Experiment Videos

  • Obese patients had significantly larger left atrial size, LV wall thickness, interventricular septal thickness, and LV mass.
  • The radius-to-wall thickness ratio was significantly smaller in the obese group.
  • Conclusions:

    • Left ventricular size and function were comparable between obese and non-obese pregnant patients.
    • Significant left ventricular hypertrophy was observed in obese patients.
    • Cardiac remodeling may play a role in maintaining LV function in obese pregnancy, but the specific role of pregnancy versus obesity requires further investigation.