Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Alcohol and white matter development--a review

F E Lancaster1

  • 1Department of Biology, Texas Woman's University, Denton 76204.

Alcoholism, Clinical and Experimental Research
|June 1, 1994
PubMed
Summary

Alcohol exposure harms developing white matter, a vulnerability known for years. Emerging technologies highlight glial cells

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Determination of benzidine in the food colours tartrazine and sunset yellow FCF, by reduction and derivatization followed by high-performance liquid chromatography.

Food additives and contaminants·2001
Same author

Dissociation between the time course of ethanol and extracellular dopamine concentrations in the nucleus accumbens after a single intraperitoneal injection.

Alcoholism, clinical and experimental research·2000
Same author

Gender differences in blood levels, but not brain levels, of ethanol in rats.

Alcoholism, clinical and experimental research·1999
Same author

Sex differences in voluntary drinking by Long Evans rats following early stress.

Alcoholism, clinical and experimental research·1998
Same author

Physical and motor development in male and female rat offspring prenatally exposed to gamma radiation.

Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes·1997
Same author

Sex differences in alcohol preference and drinking patterns emerge during the early postpubertal period.

Alcoholism, clinical and experimental research·1996

Area of Science:

  • Neuroscience
  • Developmental Biology
  • Toxicology

Background:

  • Developing white matter is highly vulnerable to alcohol exposure.
  • Previous research on alcohol's effects on white matter was limited by technological constraints.
  • Recent advancements allow detailed study of glial cells in brain development.

Purpose of the Study:

  • To review the literature on alcohol's impact on white matter development.
  • To highlight the role of new technologies in understanding this relationship.
  • To emphasize the importance of glial cells in alcohol-induced developmental neurotoxicity.

Main Methods:

  • Literature review of human and animal studies.
  • Analysis of technological advancements in neurobiology.
  • Focus on recent research utilizing new imaging and cellular analysis techniques.

Main Results:

  • Consistent evidence shows alcohol's detrimental effects on white matter development.
  • New technologies reveal neurotransmitter receptors and ion channels on glial cells.
  • Glial cells are increasingly recognized as key players in alcohol's neurotoxic effects during development.

Conclusions:

  • Glial cells represent a critical area for future research into alcohol's developmental neurotoxicity.
  • Advancements in technology are crucial for understanding alcohol's complex effects on the developing brain.
  • Further investigation is needed to elucidate the precise mechanisms by which alcohol impacts glial cell function and white matter integrity.

Related Experiment Videos