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Updated: Aug 19, 2026

Recording Brain Electromagnetic Activity During the Administration of the Gaseous Anesthetic Agents Xenon and Nitrous Oxide in Healthy Volunteers
Published on: January 13, 2018
[Use of nitrous oxide as a component of general anesthesia monitored by pulse oximetry during one-lung ventilation]
Abstract:
Pulse oximetry was employed to monitor the arterial blood oxygenation during surgery of 300 patients with pulmonary carcinomas. N2O2 anesthesia in 2:1 ratio was administered to all the patients. Change for one-lung ventilation did not lead to changes of SpO2 in 59% of the patients, whereas in 41% of the patients this value reduced below 93%. Change of the gas ratio to 1:1 in 35% of the cases was found sufficient to elevate the SpO2 value to the norm and only in 6% of the patients N2O2 had to be excluded from the anesthesia scheme for the period of one-lung ventilation and artificial ventilation with pure oxygen had to be resorted to.
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