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[Experimental renal transplantation of cirrhotic donors. I. Morphologic, immunofluorescence, and ultrastructural
J M Fernández Gómez1, T Concepción Masip, J F Val Bernal
1Servicio de Urología, Residencia Covadonga, Hospital Central de Asturias, España.
Archivos Espanoles De Urologia
|June 1, 1994
Abstract:
The cirrhotic kidney can be successfully transplanted into healthy recipients. The histological lesions have not been well defined or correlated with the functional changes observed in cirrhosis. Methods to induce experimental cirrhosis in the rat that reliably reproduce this disease have been developed. The development of microsurgical techniques have made it possible to perform transplantation in the rat. We analyzed the renal lesions of cirrhotic rats and the evolution of the graft after transplantation into a healthy rat.