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Related Experiment Videos

New approach to aortic dissection: development of an insertable aortic prosthesis

H Yoshida1, K Yasuda, T Tanabe

  • 1Department of Cardiovascular Surgery, Hokkaido University, Sapporo, Japan.

The Annals of Thoracic Surgery
|September 1, 1994
PubMed
Summary

A novel shape-memory aortic prosthesis (SAP) offers a minimally invasive solution for aortic repair. This device, made of nitinol and polyurethane, shows promise for treating aortic dissections effectively.

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Area of Science:

  • Biomaterials Science
  • Cardiovascular Surgery
  • Medical Devices

Background:

  • Aortic dissections require effective and minimally invasive treatment options.
  • Current aortic repair techniques can be complex and invasive.

Purpose of the Study:

  • To develop and evaluate a novel shape-memory aortic prosthesis (SAP) for percutaneous aortic repair.
  • To assess the feasibility and efficacy of the SAP in a canine model.

Main Methods:

  • The shape-memory aortic prosthesis (SAP) was designed using a nitinol stent and polyurethane tube.
  • SAP was compressed within a 14F catheter at low temperatures and expanded at body temperature.
  • Sutureless grafting and percutaneous placement techniques were tested in canine models, including Stanford type B dissection models.

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Main Results:

  • The SAP functioned satisfactorily for over 3 months in canine descending aorta models when the correct diameter was used.
  • A percutaneous placement technique for the SAP was successfully developed and tested.
  • The SAP was effectively used to close the entry point in Stanford type B dissection models.

Conclusions:

  • The shape-memory aortic prosthesis (SAP) is a viable option for sutureless aortic repair.
  • The percutaneous delivery system for the SAP is feasible and effective.
  • The SAP holds significant potential for emergency treatment of human aortic dissections.