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Carcinoid heart disease: early failure of an allograft valve replacement
S K Ohri1, J B Schofield, H Hodgson
1Department of Surgery, Hammersmith Hospital, Royal Postgraduate Medical School, London, England.
The Annals of Thoracic Surgery
|October 1, 1994
Abstract:
A woman who had carcinoid syndrome and carcinoid heart disease underwent tricuspid and pulmonary valve replacements with a xenograft and a cryopreserved allograft, respectively. Within 3 months of the operation severe pulmonary regurgitation and pulmonary hypertension refractory to medical therapy developed. Autopsy found the biomechanical tricuspid valve to be free of disease but the allograft in the pulmonary position was involved by carcinoid heart disease in a fashion similar to the excised native pulmonary valve.