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[3-Substituted 2-phenylindoles: synthesis and biological properties]
S Mahboobi1, G Grothus, E von Angerer
1Institut für Pharmazie der Universität Regensburg.
Archiv Der Pharmazie
|August 1, 1994
Summary
This study synthesized novel indole derivatives and found that several compounds exhibit estrogen receptor affinity and inhibit the growth of breast cancer cells (MCF-7 and MDA-MB-231). Structure-activity relationships were also explored.
Area of Science:
- Organic Chemistry
- Medicinal Chemistry
- Pharmacology