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Gene expression of VIP receptor in rat lymphocytes
R P Gomariz1, E Garrido, J Leceta
1Departamento Biologia Celular, Facultad de Biologia, Universidad Complutense, Madrid, Spain.
Biochemical and Biophysical Research Communications
|September 30, 1994
Abstract:
In the present report we analyze by reverse transcription (RT) and polymerase chain reaction (PCR) the expression of vasoactive intestinal peptide receptors (VIP-R) in rat thymocytes and peripheral T and B lymphocytes. We have obtained a specific VIP-R cDNA product of 311 bp identical in size to that obtained from lung. These results have been confirmed by Southern hybridization analysis. VIP receptor gene expression in central and peripheral lymphoid organs support the notion that VIP is a immunomodulatory peptide.