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Anticardiolipin and acquired protein S deficiency in early childhood
1University of Adelaide Department of Paediatrics, Adelaide Children's Hospital, Australia.
Journal of Paediatrics and Child Health
|August 1, 1994
Insights
A child experienced hemiplegia due to deep cerebral venous thrombosis, which resolved with warfarin treatment. The condition was linked to high anticardiolipin antibodies and protein S deficiency.
Area of Science:
- Neurology
- Pediatrics
- Hematology
Background:
- Deep cerebral venous thrombosis (DCVT) is a rare but serious condition in children.
- Cerebral venous thrombosis can lead to significant neurological deficits such as hemiplegia.
- Identifying underlying causes is crucial for effective management and prevention of recurrence.
Abstract:
A 27 month old child presented with left hemiplegia and was found to have deep cerebral venous thrombosis. The deep cerebral venous thrombosis resolved on warfarin. Elevated and fluctuating anticardiolipin antibodies as well as protein S deficiency were detected.