Pressure-volume relationships of the respiratory system in normal cats

We studied the pressure-volume (PV) relationships of the total respiratory system, lung and chest wall in 8 anesthetized and paralyzed normal adult cats. The PV relationships of the total respiratory system had a sigmoid shape with a relatively linear portion with an alveolar pressure between 0 to +15 cmH2O. The relative impact of the lung and chest wall to the total elastic recoil forces of the respiratory system was approximately equal within a physiological pressure range. The results suggest that measurements of PV relationships of the respiratory system may offer a physiologic basis for accurate interpretation of pulmonary functions, leading to a better therapeutic strategy in animals with lung diseases.