[Methods for the superselective radioembolization of liver tumors with 90yttrium-resin particles]

An improved technique for radioembolization of non-resectable liver tumours is described. 90yttrium-labelled Bio-Rex-70 particles which show high stability and good tissue tolerance are applied superselectively via the tumour-feeding artery using a microcatheter. The procedure includes both diagnostic and therapeutic angiography. Angiography is complemented by angioscintigraphy (99mTc-MAP) and an i.v. 99mTc-colloid scan of the liver. Thus it is possible pretherapeutically to evaluate tumour volume and dose distribution both in and outside of the liver, and in the lung due to shunt. These estimates were re-evaluated posttherapeutically. Radioembolization can thus be quantified and the doses absorbed by the tumour as well as the liver and lung can be calculated.