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Pseudoxanthoma-elasticum-like papillary dermal elastolysis: another case

A Patrizi1, I Neri, P Trevisi

  • 1Department of Dermatology, University of Bologna, Italy.

Dermatology (Basel, Switzerland)
|January 1, 1994
PubMed
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Pseudoxanthoma-elasticum-like papillary dermal elastolysis is a rare skin condition affecting aged females. This disorder involves the loss of elastic fibers in the skin, causing characteristic lesions.

Area of Science:

  • Dermatology
  • Pathology

Background:

  • Pseudoxanthoma-elasticum-like papillary dermal elastolysis (PXE-PDE) is a rare, acquired, idiopathic, non-inflammatory elastolytic disorder.
  • It primarily affects aged females, presenting with asymptomatic skin lesions on the neck and supraclavicular areas.

Observation:

  • The clinical presentation of PXE-PDE can mimic pseudoxanthoma elasticum.
  • The characteristic histopathological finding is a complete absence of elastic fibers in the papillary dermis.

Findings:

  • This report details a case of PXE-PDE in a 69-year-old Italian woman.
  • Histological examination confirmed the total loss of elastic fibers in the papillary dermis.

Implications:

  • This case contributes to the understanding of PXE-PDE prevalence and clinical spectrum.

Related Experiment Videos

  • Further research may elucidate the underlying mechanisms and potential therapeutic targets for this rare elastolytic disorder.