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Preparation of Decellularized Kidney Scaffolds in Rats

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Published on: March 18, 2021

[Changes in bone mineral content in kidney deficiency]

X J Cai¹, Y Zhang, S L Huang

¹210 Hospital, Dalian.

Zhongguo Zhong Xi Yi Jie He Za Zhi Zhongguo Zhongxiyi Jiehe Zazhi = Chinese Journal of Integrated Traditional and Western Medicine

|March 1, 1994

Summary

Bone mineral density (BMD) is lower in patients with Kidney Deficiency (KD) compared to those without KD or the normal group. This study confirms characteristic BMD changes in KD patients, supporting Traditional Chinese Medicine (TCM) syndrome objectivity.

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Area of Science:

Orthopedics
Nephrology
Traditional Chinese Medicine (TCM)

Background:

Kidney Deficiency (KD) is a concept in Traditional Chinese Medicine (TCM) that may impact bone health.
Bone mineral density (BMD) is a key indicator of bone health and osteoporosis risk.

Purpose of the Study:

To investigate bone mineral density (BMD) in the ulna and radius of patients with and without Kidney Deficiency (KD).
To determine if KD is associated with characteristic changes in BMD.
To explore the objective evidence for KD syndromes in TCM.

Main Methods:

Assayed bone mineral determination (BMD) of the ulna and radius.
Compared BMD values in 184 patients categorized into three groups: with KD, without KD, and a normal control group.

Main Results:

Patients with KD exhibited significantly lower BMD in the ulna and radius compared to both the group without KD and the normal control group.
No significant difference in BMD was observed between patients without KD and the normal control group.
A significant difference in BMD was found between patients with the same underlying condition but with versus without KD.

Conclusions:

Bone mineral density (BMD) shows characteristic changes in patients with Kidney Deficiency (KD).
The findings provide objective evidence supporting the concept of KD syndromes within Traditional Chinese Medicine (TCM).
KD is associated with reduced bone mineral density, highlighting potential implications for bone health management.